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. 2020 Dec 21;42(4):601–610. doi: 10.1093/carcin/bgaa140

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© The Author(s) 2020. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 6. — Hsa_circ_002144 promoted malignant behaviors of CRC through miR-615-5p-mediated LARP1. (A) The influence of hsa_circ_002144 and miR-615-5p on protein expression of LARP1 and mTOR in T84 and Lovo cells detected by western blot. (B) The influence of hsa_circ_002144 and LARP1 on cell viability of T84 cells detected by CCK8. (C) The influence of hsa_circ_002144 and LARP1 on cell proliferation of T84 cells detected by colony formation assay. (D) The influence of hsa_circ_002144 and LARP1 on cell apoptosis of T84 cells detected by flow cytometry. (E) The influence of hsa_circ_002144 and LARP1 on cell migration of T84 cells detected by wound healing assay. (F) The influence of hsa_circ_002144 and LARP1 on cell invasion of T84 cells detected by transwell assay. *P < 0.05, **P < 0.01, ***P < 0.001.