Table 15.
Concordance between ECHA and CATMoS data sets for the categorical end points.
VT | NT | EPA | GHS | |
---|---|---|---|---|
Sn* | 0.34 | 0.98 | 0.70 | 0.56 |
Sp* | 1.00 | 0.86 | 0.93 | 0.96 |
BA | 0.67 | 0.92 | 0.82 | 0.76 |
*Sn and Sp of ECHA calculated based on CATMoS data.
Note: BA, balanced accuracy; CATMoS, Collaborative Acute Toxicity Modeling Suite; ECHA, European Chemicals Agency; EPA, U.S. Environmental Protection Agency; GHS, U.N. Globally Harmonized System of Classification and Labeling of Chemicals; , lethal dose, 50% or dose of a substance that would be expected to kill half the animals in a test group; NT, nontoxic/toxic; Sn, sensitivity or true negative rate; Sp, specificity or true positive rate; VT, very toxic/not very toxic.