Skip to main content
. 2021 Apr 30;129(4):047013. doi: 10.1289/EHP8495

Table 15.

Concordance between ECHA and CATMoS data sets for the categorical end points.

VT NT EPA GHS
Sn* 0.34 0.98 0.70 0.56
Sp* 1.00 0.86 0.93 0.96
BA 0.67 0.92 0.82 0.76

*Sn and Sp of ECHA calculated based on CATMoS data.

Note: BA, balanced accuracy; CATMoS, Collaborative Acute Toxicity Modeling Suite; ECHA, European Chemicals Agency; EPA, U.S. Environmental Protection Agency; GHS, U.N. Globally Harmonized System of Classification and Labeling of Chemicals; LD50, lethal dose, 50% or dose of a substance that would be expected to kill half the animals in a test group; NT, nontoxic/toxic; Sn, sensitivity or true negative rate; Sp, specificity or true positive rate; VT, very toxic/not very toxic.