Table 20.

Evaluation parameters for the U.S. EPA category predictions for the curated in vivo data set.

	Step 1: End point					Step 2: WoE
	I	II	III	IV	Overall	I	II	III	IV	Overall
BA	0.84	0.81	0.79	0.67	0.78	0.93	0.79	0.79	0.67	0.80
Sn	0.70	0.76	0.84	0.36	0.66	0.88	0.72	0.84	0.36	0.70
Sp	0.99	0.86	0.75	0.98	0.89	0.99	0.87	0.75	0.98	0.90

Note: Corresponding confusion matrices available in Supplemental Material 9. BA, balanced accuracy; EPA, U.S. Environmental Protection Agency; Sn, sensitivity or true negative rate; Sp, specificity or true positive rate; WoE, weight of evidence.