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. 2021 Mar 3;18(176):20201013. doi: 10.1098/rsif.2020.1013

Figure 2.

Figure 2.

Species-scaled predicted delivery rates to non-tumour tissue in organs in humans, rats and mice. Rates are normalized so that the sum across organs for each species is 100. See table 1 for a comparison of absolute rates. Scatter points and bar extents indicate the mean and standard deviation of delivery rates over 100 repeats, with each repeat using different random fractional blood flows and volumes, uniformly drawn from experimental data in the literature. Text labels give the ratio of mean predicted delivery rates in rats and mice to human rates. The relative distribution of rates across the major organs differs by species, and, consequently, inter-species scaling of delivery rates is organ-specific. Note that the horizontal axis is a log scale.