Fig 5. Benznidazole reduces DNA damage developing an adaptive response to HeLa cells.

Comet assay was performed in (A) Infected HeLa cells, (B) cells treated with H₂O₂ (20 μm), or (C) Infected AC16 cells that were pretreated or not with 100 μm or 200 μm Benznidazole (BNZ). Scatter plots from tail moment quantification of 3 independent experiments (100 cells per experiment) were performed.**p<0.01; ***p<0.001. Isolated chromatin from infected cells or not that were pretreated or not with BNZ (200μm) were immunoblotted with (E) anti-PAR (F) anti-OGG1. Histone 3 was used as a loading control.