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. 2021 Apr 30;15(4):e0009037. doi: 10.1371/journal.pntd.0009037

Table 1. Demographic and clinical characteristics of cases of SFTS human-to-human transmission in China and South Korea, 1996–2019.

Characteristics Index cases (n = 27) Secondary cases (n = 111) χ2 t P
Demographic features
Sex, male 16(n = 27) 65(n = 93) 1.08 N/A 0.30
Age, y 65.35±8.14(n = 26) 51.76±13.35(n = 82) N/A 4.90 <0.01
Age>65y 12(n = 26) 13(n = 82) 10.18 N/A <0.01
Farmer 23(n = 24) 54(n = 94) 12.43 N/A <0.01
Time from onset to treatment, d 4.00±2.81(n = 26) 3.31±1.92(n = 45) N/A 976.50* 0.62
Time from onset to admission, d 5.57±3.02(n = 26) 3.31±1.92(n = 45) N/A 3.87 <0.01
General symptoms
Fever 27(n = 27) 96(n = 106) 1.57 N/A 0.21
Fatigue 13(n = 18) 43(n = 64) 0.16 N/A 0.69
Headache 10(n = 17) 37(n = 79) 0.81 N/A 0.37
Myalgia 13(n = 18) 61(n = 85) 0.002 N/A 0.97
Gastrointestinal symptoms 23(n = 24) 53(n = 93) 12.65 N/A <0.01
Respiratory symptoms 17(n = 19) 25(n = 62) 14.07 N/A <0.01
CNS manifestation 18(n = 21) 10(n = 70) 38.69 N/A <0.01
Hemorrhagic symptoms 23(n = 24) 17(n = 90) 49.25 N/A <0.01
MODS 16(n = 19) 6(n = 69) 45.31 N/A <0.01
Fatal outcome 27(n = 27) 10(n = 110) 90.89 N/A <0.01

Note: CNS is central nervous system, MODS is multi organ dysfunction syndrome, and n is the total number of cases for which information is available

* is T value (Wilcoxon W Test), y is year, d is day.