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. Author manuscript; available in PMC: 2021 Apr 30.
Published in final edited form as: Ann Neurol. 2020 Oct 13;88(6):1178–1193. doi: 10.1002/ana.25906

FIGURE 2:

FIGURE 2:

Test–retest reliability of subthalamic nucleus deep brain stimulation (DBS)-induced functional magnetic resonance imaging (fMRI) responses across time. To evaluate reliability, data from each postsurgical DBS treatment visit were partitioned into 2 halves and fMRI responses were modeled using a boxcar function by contrasting the ON and OFF blocks. Test (left) and retest (right) results of an exemplar patient (Patient 13) illustrate blood oxygen level–dependent signal activations and deactivations in response to high-frequency (top panel) and low-frequency (bottom panel) DBS stimulation at the 1-, 3-, 6-, and 12-month follow-up visits.