Fig. 5. AuNP intracellular localization. To assess if 26 nm AuNPs are phagocytosed by DCs and if they can change the cellular phenotype at the ultrastructural level, moDCs were treated with the following stimuli and subsequently prepared for TEM inspection. (A-Aii) Untreated control, (B-Bii) LPS control; (C-Cii) 26 nm AuNPs; (D-Dii) 26 nm AuNPs + LPS. Black asterisks, endosomes; white asterisks, autophagic structures; black star, class E-like compartment; white arrowheads, “frustrated” MVBs.
