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. 2020 Dec 23;76(5):885–892. doi: 10.1093/gerona/glaa315

Table 2.

Relationship Between Frailty Index and Hemodynamic Function Within 30 Seconds of Standing Estimated by Statistical Parametric Mapping

Clusters Association of Frailty Index
Univariate Regression Multivariate Regression
Temporal Range (s) Duration (s) t Value p Value Temporal Range (s) Duration (s) t Value p Value
Heart rate 1 0.9–19.3 18.5 −2.56 .0005 0.8–17.5 16.6 −2.56 0.0011
Systolic blood pressure 2 4.7–13.2 8.5 2.54 .0218 5.3–15.6 10.2 2.54 0.0149
18.4–24.4 6.0 −2.54 .0328
Tissue saturation index 1 17.7–29.0 11.3 −2.48 .0199 20.1–26.9 6.8 −2.47 0.0363

Notes: The alpha level was set at 0.05 for all analysis and specific p values are reported for each significant region of the curve analyzed. Univariate regression considered the association of higher frailty index on dependent variables. Multivariate regressions used the same model with the addition of covariates sex, age, and an age-squared term (to account for potentially nonlinear association with age). Temporal range is consistent with the period following standing (in seconds) over which significant differences between curves were identified. Extent is analogous with duration of the significant region of the curve.