FIGURE 1.

Experimental flowchart. Mice were divided into four groups: the control group, model group, Xiaoyaosan treatment group, and probiotics treatment group. The model group received oral ampicillin solution for 14 consecutive days at a dose of 100 mg/kg and an intragastric volume of 0.1 ml/10 g body weight. The control group received oral saline in an equivalent volume and served as a negative control. Mice in the two treatment groups received Xiaoyaosan (0.658 g/kg/d) and probiotics solution (0.15 ml/d), respectively.