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Effects of Xiaoyaosan on the NLRP3-ASC-CASPASE-1 immunolabeling in the colon. (A) Immunohistochemical staining of NLRP3, ASC and CASPASE-1 protein in colon (scale bar = 50 mm, ×400 magnification). (B) Expression. of NLRP3 in colon. (C) Expression of ASC in colon. (D) Expression of CASPASE-1 in colon. n = 6 per group. Data are expressed as the mean ± SEM. *p < 0.05, **p < 0.01 vs. the control group; # p < 0.05, ## p < 0.01 vs. the antibiotic-induced model group.
