Table 3. Binding constants (Ka,M−1) of the protein variants with model DPPC SUVs as obtained from the FCS study for WT SOD1 and all the mutants.
Systems | Asssociation constants (Ka,M−1) |
---|---|
WT SOD1 + DPPC SUV | (4.1 ± 0.1) × 106 |
H121F + DPPC SUV | (5.2 ± 0.2) × 106 |
H72F + DPPC SUV | (9.6 ± 0.4) × 107 |
apo + DPPC SUV | (9.8 ± 0.1) × 107 |
G37R-DPPC SUV | (2.2 ± 0.3) × 106 |
I113T-DPPC SUV | (8.8 ± 0.2) × 106 |