Table 1.
General characteristics.
| Characteristics | Stroke patients (n = 50) | Healthy controls (n = 50) | p 1 |
|---|---|---|---|
| Male sex, % (n) | 70.00 (35) | 28.00 (14) | <0.01 |
| Age, years, mean ± SD | 63.20 ± 12.00 | 57.36 ± 10.65 | 0.01 |
| Overweight or obesity, % (n) | 32.00 (16) | 20.00 (10) | 0.43 |
| Smoking, % (n) | 38.00 (19) | 4.00 (2) | <0.01 |
| Alcohol, % (n) | 32.00 (16) | 10.00 (5) | <0.01 |
| Diabetes, % (n) | 42.00 (21) | 8.00 (4) | <0.01 |
| Hypertension, % (n) | 72.00 (36) | 26.00 (13) | <0.01 |
| Volume of acute cerebral infarction, mm3, mean ± SD | 25.02 ± 49.50 | 0.68 ± 0.82 | <0.01 |
| Area of carotid artery plaque, mm2, mean ± SD | 61.42 ± 44.27 | 60.67 ± 42.71 | 0.95 |
| TMAO, ng/mL, mean ± SD | 2659.51 ± 976.81 | 1484.75 ± 648.87 | <0.01 |
| Lp-a, g/L, mean ± SD | 131.52 ± 90.83 | 33.38 ± 10.50 | <0.01 |
| Apo-A1, g/L, mean ± SD | 1.04 ± 0.22 | 1.18 ± 0.26 | <0.01 |
| Apo-B, g/L, mean ± SD | 1.00 ± 0.26 | 0.83 ± 0.28 | <0.01 |
| Apo-A1/B ratio, mean ± SD | 1.03 ± 0.27 | 1.43 ± 0.42 | <0.01 |
| TC, mmol/L, mean ± SD | 4.70 ± 1.12 | 4.37 ± 0.81 | 0.12 |
| HDL-C, mmol/L, mean ± SD | 1.02 ± 0.25 | 1.16 ± 0.28 | <0.01 |
| LDL-C, mmol/L, mean ± SD | 2.91 ± 1.02 | 2.57 ± 0.80 | 0.07 |
| TG, mmol/L, mean ± SD | 1.78 ± 1.08 | 1.49 ± 0.76 | 0.16 |
| D-Dimer, IU/L, mean ± SD | 0.88 ± 0.84 | 0.48 ± 0.33 | <0.01 |
| TT, s, mean ± SD | 16.01 ± 0.88 | 16.15 ± 0.89 | 0.37 |
Abbreviations: SD: standard deviation; TMAO: trimethylamine N-oxide; Lp-a: lipoprotein-a; Apo-A1: apolipoprotein A1; Apo-B: apolipoprotein B; TC: total cholesterol; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; TG: triglycerides; TT: thrombin time. 1p value was obtained using chi-square tests or Fisher's exact tests for categorical variables and Mann-Whitney U tests for continuous variables.