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. 2021 Apr 16;11:659676. doi: 10.3389/fonc.2021.659676

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Copyright © 2021 Hu, Cai, Zhao, Zhong and Gong

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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ML-098 recovered the invasion and migration abilities of Lv-HNRNPC group cells in part. (A, B) Transwell assay demonstrating the recovered efficiency of ML-098 in Lv-HNRNPC group cell invasion. (C, D) Scratch wound test showing the rescue by ML-098 of cell migration in the Lv-HNRNPC group. (E, F) Western blot to detect the recovery of EMT process in Lv-HNRNPC cell groups after treatment with ML-098. Each test was repeated independently in triplicate, and the results were demonstrated as mean ± standard deviation (SD). ^*P < 0.05, ^**P < 0.01, ^***P < 0.001, for Lv-NC+DMSO group compared with Lv-HNRNPC+ML-098 group; ^#P < 0.05, ^##P < 0.01, for Lv-HNRNPC+DMSO group compared with Lv-HNRNPC+ML-098 group.