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. 2021 May 1;24(6):102489. doi: 10.1016/j.isci.2021.102489

Figure 4.

Figure 4

Inpatients in the ICU have increased antibodies reactive to Spike and RBD proteins

(A) Pie chart highlighting the fraction of SARS-CoV-2-infected patients seen at the MUSC hospital as outpatients (n = 46), inpatients (n = 27), and inpatient ICU (n = 21).

(B–D) (B) SARS-CoV-2-infected patient serum analyzing percent ACE2 blockade. SARS-CoV-2-infected patient serum samples were analyzed for IgG, IgM, and IgA antibodies against SARS-CoV-2 Spike (C) and RBD (D) using ELISA. Data are represented as the mean ± SEM. One-way ANOVA analyzed data with Tukey's multiple comparisons test. ∗p<0.05, ∗∗p<0.01, ∗∗∗p<0.001, ∗∗∗∗p<0.0001.