Table 1.
Summary of patient characteristics1
| Patient ID | Visit | Age | Sex | Urine Gd Pre-CT | Urine Gd Post-CT | Flare Severity | Control | Batch | Years since GBCA | Years Since Onset | # MRIs |
|---|---|---|---|---|---|---|---|---|---|---|---|
| P01 | V1 | 59 | M | 0.5 | 23 | 0 | yes | 1 | 4 | 0 | 15 |
| P01 | V2 | 59 | M | 0.5 | 31 | 0 | yes | 1 | 4.3 | 0 | 15 |
| P02 | V1 | 48 | F | 0.7 | 34 | 8 | no | 1 | 2 | 10 | 17 |
| P02 | V2 | 48 | F | 0.4 | 14 | 5 | no | 1 | 2.3 | 10 | 17 |
| P03 | V1 | 28 | F | 0 | 5.6 | 5 | no | 1 | 0.3 | 0.3 | 2 |
| P03 | V2 | 28 | F | 0.3 | 5.1 | 4 | no | 1 | 0.6 | 0.6 | 2 |
| P04 | V1 | 44 | F | 0.2 | 4.7 | 5 | no | 1 | 1 | 1 | 3 |
| P04 | V2 | 44 | F | 0 | 5.1 | 4 | no | 2 | 1.3 | 1 | 3 |
| P05 | V1 | 55 | F | 0.4 | 25 | 7 | no | 1 | 2 | 7 | 7 |
| P05 | V2 | 55 | F | 0.4 | 28 | 7 | no | 2 | 2.3 | 7.3 | 13 |
| P07 | V1 | 66 | M | 0.2 | 17 | 4 | no | 1 | 2 | 7 | 3 |
| P07 | V2 | 66 | M | 2 | 10 | 3 | no | 2 | 2.3 | 7.3 | 3 |
| P09 | V1 | 59 | F | 0.9 | 29 | 7 | no | 1 | 0.3 | 4 | 5 |
| P09 | V2 | 59 | F | 0.3 | 20 | 7 | no | 2 | 0.6 | 4.3 | 5 |
| P10 | V1 | 49 | M | 0.7 | 25 | 6 | no | 1 | 0.3 | 0.5 | 2 |
| P11 | V1 | 21 | F | 0.3 | 12 | 7 | no | 1 | 5 | 13 | 15 |
| P12 | V1 | 60 | F | 0.5 | 8.7 | 9 | no | 1 | 0.3 | 0.3 | 1* |
| P13 | V1 | 44 | F | 0.5 | 31 | 7 | no | 1 | 0.2 | 1 | 7 |
| P14 | V1 | 36 | M | 72 | 68 | 5 | no | 1 | 0.1 | 2 | 15 |
| P15 | V1 | 44 | F | 0.4 | 9.1 | 6 | no | 1 | 0.8 | 7 | 2 |
| P16 | V1 | 59 | M | 0 | 5.7 | 5 | no | 1 | 4 | 14 | 2 |
| P17 | V1 | 66 | M | 0 | 15 | 0 | yes | 1 | 0.5 | 0 | 2 |
| P18 | V1 | 57 | F | 1.4 | 4.9 | 8 | no | 1 | 0.2 | 1 | 4 |
| P19 | V1 | 32 | F | 10 | 12 | 5 | no | 1 | 0.2 | 0.3 | 2* |
| P20 | V1 | 56 | M | 0 | 3.6 | 0 | yes | 2 | 11 | 0 | 1 |
| P21 | V1 | 61 | F | 0 | 2.2 | 5 | no | 2 | 1.5 | 1.8 | 5 |
| P22 | V1 | 47 | M | 0 | 4.6 | 4 | no | 2 | 2.5 | 3.5 | 3 |
| P23 | V1 | 44 | F | 0.3 | ? | 8 | no | 2 | 0.8 | 2.4 | 6 |
| P24 | V1 | 48 | F | 4.9 | 12 | 7 | no | 2 | 0.3 | 0.3 | 2* |
| P25 | V1 | 50 | M | 0.6 | 4.7 | 5 | no | 2 | 0.2 | 0.4 | 6* |
| P26 | V1 | 36 | F | 0.1 | 0.7 | 4 | no | 2 | 0.3 | 0.3 | 1* |
1
Patient ID numbers are discontinuous between PO5 and P07. Visit = first or fifth Ca-DTPA chelation therapy session. Gd = gadolinium. Urine Gd = 24-hour urine Gd content. Flare severity = the patient’s Flare rating 24 hours after the visit. Control = Gadolinium Storage Condition patient. Batch refers to the first and the second Luminex Cytokine immunoassay. GBCA = Gadolinium Based Contrast Agent. Years Since GBCA = number of years since receiving the most recently administered GBCA dose. Years Since Onset = number of years since GDD symptom onset. # MRIs = number of GBCA MRIs the patient had received.
*
= received only a macrocyclic GBCA.