Table 2.
Cytokines with a significant difference between GDD patients and healthy Flu vaccine controls1
| Cytokine | P-value, GDD vs. Control | GDD Mean | GDD SD | Control Mean | Control SD | Difference in Means as Pct of Control Range | P-value, Recent onset vs. Control | Recent Onset Mean | Recent Onset SD |
|---|---|---|---|---|---|---|---|---|---|
| MIP1D | 0.000001 | 2803.6 | 1467.3 | 1023.9 | 517.5 | 72.8 | 0.001497 | 3009.2 | 1853.7 |
| SCD40L | 0.000001 | 1547.0 | 1389.4 | 3539.1 | 1495.6 | −29.3 | 0.000031 | 1644.5 | 1116.4 |
| CTACK | 0.000007 | 6287.9 | 1386.1 | 4636.5 | 1149.3 | 33.5 | 0.000001 | 6755.6 | 1046.3 |
| TRAIL | 0.001790 | 202.2 | 47.8 | 158.3 | 57.8 | 15.7 | 0.026655 | 197.1 | 50.1 |
| GCSF | 0.001936 | 230.2 | 66.2 | 180.0 | 49.8 | 25.5 | 0.107031 | 219.4 | 80.8 |
| PAI1 | 0.004547 | 25576.6 | 4070.5 | 28709.6 | 4229.3 | −15.8 | 0.051418 | 26026.1 | 4110.5 |
| EGF | 0.004884 | 257.4 | 368.0 | 511.9 | 291.5 | −24.2 | 0.000006 | 211.2 | 119.9 |
| GROA | 0.009568 | 6612.9 | 5920.8 | 3289.8 | 2341.9 | 34.7 | 0.053633 | 7107.3 | 6629.4 |
| EOTAXIN2 | 0.019041 | 3295.5 | 2926.4 | 1786.6 | 1453.4 | 22.2 | 0.172307 | 2844.0 | 2615.0 |
| HGF | 0.037928 | 28.8 | 10.9 | 34.5 | 9.6 | −14.1 | 0.000149 | 25.9 | 4.7 |
| IFNA2 | 0.042243 | 24.4 | 5.9 | 28.4 | 9.2 | −10.6 | 0.154038 | 24.9 | 6.7 |
| IL12P70 | 0.042394 | 25.7 | 6.6 | 31.6 | 14.8 | −10.3 | 0.142343 | 26.8 | 7.5 |
1
Columns include cytokine, the p-value for the comparison between GDD patients and controls, the mean levels and standard deviations for both GDD patients and controls, the difference in means between GDD patients and controls expressed as a percentage of the control range, the p-value of a comparison of recent onset GDD patients (≤ 2years) to the controls, and the mean levels and standard deviations for the recent onset GDD patients. P-values are from Student’s t-test.
2
Serum samples.