Table 2.
EdgeR report of differentially expressed genes 18 h post-treatment with 1 µM FH-1321.
| GeneID | Name | log2 fold change | log2 counts per million | F value | p value | False discovery rate |
|---|---|---|---|---|---|---|
| ENSG00000154277 | UCHL1 | −4.565471687 | −0.206793672 | 38.67266739 | 5.05E−10 | 3.31E−06 |
| ENSG00000261409 | AL035425.3 | −4.424650789 | 0.138068277 | 48.33716477 | 3.63E−12 | 3.52E−08 |
| ENSG00000138829 | FBN2 | −4.131894042 | −0.10684436 | 38.38083941 | 5.86E−10 | 3.42E−06 |
| ENSG00000116962 | NID1 | −3.999181717 | −0.658930046 | 22.77369298 | 1.83E−06 | 0.0053254 |
| ENSG00000117114 | ADGRL2 | −3.832053102 | −0.731611642 | 20.4765316 | 6.05E−06 | 0.0125945 |
| ENSG00000159217 | IGF2BP1 | −3.68912559 | 0.398606752 | 48.96044087 | 2.64E−12 | 3.08E−08 |
| ENSG00000229807 | XIST | −3.488985213 | 4.901654584 | 651.1533715 | 7.66E−143 | 4.47E−138 |
| ENSG00000038427 | VCAN | −3.429296401 | −0.658534387 | 18.19677341 | 2.00E−05 | 0.0323138 |
| ENSG00000154734 | ADAMTS1 | −3.363272907 | 0.603352768 | 54.52344803 | 1.56E−13 | 2.27E−09 |
| ENSG00000212402 | SNORA74B | −3.359506375 | 0.031288549 | 24.79248338 | 5.34E−06 | 0.0115336 |
| ENSG00000145147 | SLIT2 | −3.051459541 | 0.34517457 | 38.64546164 | 5.12E−10 | 3.31E−06 |
| ENSG00000101057 | MYBL2 | −2.996889004 | −0.083099003 | 26.07056348 | 3.34E−07 | 0.0010805 |
| ENSG00000133124 | IRS4 | −2.98565677 | 1.371029055 | 71.98000489 | 2.22E−17 | 6.48E−13 |
| ENSG00000083857 | FAT1 | −2.913815462 | −0.014539277 | 28.05815995 | 1.18E−07 | 0.0004052 |
| ENSG00000145555 | MYO10 | −2.805586002 | −0.261404374 | 22.18212809 | 2.49E−06 | 0.0066275 |
| ENSG00000139219 | COL2A1 | −2.783583292 | −0.107869982 | 24.02115361 | 9.55E−07 | 0.0029316 |
| ENSG00000201098 | RNY1 | −2.770572459 | 0.413772602 | 35.10682622 | 4.80E−09 | 2.33E−05 |
| ENSG00000135862 | LAMC1 | −2.712320987 | 0.135877854 | 28.32916412 | 1.03E−07 | 0.0003743 |
| ENSG00000102024 | PLS3 | −2.681318527 | 1.605768497 | 71.57130553 | 3.77E−17 | 7.32E−13 |
| ENSG00000096696 | DSP | −2.636756013 | 0.730407853 | 42.41260665 | 7.45E−11 | 6.21E−07 |
| ENSG00000089685 | BIRC5 | −2.490957592 | −0.234929297 | 18.96212263 | 1.34E−05 | 0.02512 |
| ENSG00000238741 | SCARNA7 | −2.387719434 | 0.361869871 | 24.20859794 | 2.61E−06 | 0.0066275 |
| ENSG00000163430 | FSTL1 | −2.380561336 | −0.26218126 | 17.71426598 | 2.57E−05 | 0.0405086 |
| ENSG00000200785 | SNORD8 | −2.299517907 | −0.084333496 | 18.58796384 | 1.64E−05 | 0.0290541 |
| ENSG00000142949 | PTPRF | −2.256619192 | 0.113519171 | 22.13114508 | 2.55E−06 | 0.0066275 |
| ENSG00000111206 | FOXM1 | −2.226389714 | 0.092218251 | 21.57249486 | 3.41E−06 | 0.0082946 |
| ENSG00000212283 | SNORD89 | −1.860714666 | 1.311190667 | 36.42603494 | 1.90E−09 | 1.01E−05 |
| ENSG00000208772 | SNORD94 | −1.822933237 | 1.022233292 | 29.05095049 | 7.20E−08 | 0.0002797 |
| ENSG00000166165 | CKB | −1.686278111 | 1.500619457 | 33.19463106 | 9.30E−09 | 4.17E−05 |
| ENSG00000046604 | DSG2 | −1.609604699 | 0.644434181 | 18.28993873 | 1.90E−05 | 0.031651 |
| ENSG00000202058 | RN7SKP80 | −1.234932643 | 1.641387087 | 21.21111392 | 4.96E−06 | 0.011119 |
| ENSG00000126016 | AMOT | −0.773124251 | 3.662624092 | 30.45093151 | 3.53E−08 | 0.0001469 |
| ENSG00000130164 | LDLR | −0.411325614 | 5.764550633 | 21.07423587 | 4.43E−06 | 0.0103253 |
| ENSG00000101745 | ANKRD12 | 0.339396244 | 7.502647544 | 18.65815618 | 1.57E−05 | 0.0285379 |
| ENSG00000170881 | RNF139 | 0.423776234 | 5.074578288 | 18.46989874 | 1.74E−05 | 0.0297963 |
| ENSG00000213757 | AC020898.1 | 0.876931574 | 2.474353677 | 19.06819338 | 1.27E−05 | 0.0246334 |
| ENSG00000198064 | NPIPB13 | 2.365643737 | 0.043629688 | 19.87731825 | 8.31E−06 | 0.0167005 |
Differential expression and p values are calculated for each gene using an exact test analogous to Fisher’s exact test adapted for overdispersed data in the EdgeR package88.