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. 2021 Apr 30;11:256. doi: 10.1038/s41398-021-01378-8

Table 5.

Top 11 clusters with their representative enriched terms (one per cluster) for the associated genes (CIPC PINX1, NKX2-2, and PTPRE) (Single tissue analysis (Brain)) and their interactors.

GO Category Description Count % Log10(P) Log10(q)
GO:0007004 GO Biological processes Telomere maintenance via telomerase 7 43.75 −13.85 −9.50
GO:0031018 GO Biological processes Endocrine pancreas development 6 26.09 −11.54 −8.33
GO:0051347 GO Biological processes Positive regulation of transferase activity 8 50.00 −8.34 −5.76
GO:0070851 GO Molecular functions Growth factor receptor binding 5 31.25 −7.69 −5.24
GO:0031647 GO Biological processes Regulation of protein stability 6 26.09 −6.61 −4.30
GO:0051098 GO Biological processes Regulation of binding 6 26.09 −6.00 −3.83
GO:0010035 GO Biological processes Response to inorganic substance 6 37.50 −5.98 −3.83
GO:0019904 GO Molecular functions Protein domain specific binding 6 37.50 −5.40 −3.36
GO:0050999 GO Biological processes Regulation of nitric−oxide synthase activity 3 18.75 −5.31 −3.29
GO:0009636 GO Biological processes Response to toxic substance 6 26.09 −5.08 −3.10
GO:0019932 GO Biological processes Second-messenger-mediated signaling 4 17.39 −3.12 −1.51

“Count” is the number of genes in the user-provided lists with membership in the given ontology term. “%“ is the percentage of all of the provided genes that are found in the given ontology term (only input genes with at least one ontology term annotation are included in the calculation). “Log10(P)” is the p-value in log base 10. “Log10(q)” is the multi-test adjusted p-value in log base 10.