Table 9.
Top 11 clusters with their representative enriched terms (one per cluster) fot the associated genes by UTMOST Cross Tissue Analysis (BLK and NKX2-2) and their predicted interactors.
| GO | Category | Description | Count | % | Log10(P) | Log10(q) |
|---|---|---|---|---|---|---|
| GO:0004713 | GO Molecular functions | Protein tyrosine kinase activity | 6 | 42.86 | −10.03 | −5.68 |
| GO:0031018 | GO Biological processes | Endocrine pancreas development | 5 | 25.00 | −9.57 | −5.64 |
| GO:0019815 | GO Cellular components | B cell receptor complex | 3 | 21.43 | −9.21 | −5.56 |
| GO:0051090 | GO Biological processes | Regulation of DNA-binding transcription factor activity | 7 | 35.00 | −7.40 | −4.63 |
| GO:0030072 | GO Biological processes | Peptide hormone secretion | 6 | 30.00 | −7.37 | −4.63 |
| GO:0007263 | GO Biological processes | Nitric oxide mediated signal transduction | 3 | 21.43 | −6.25 | −3.89 |
| GO:0048812 | GO Biological processes | Neuron projection morphogenesis | 7 | 35.00 | −6.21 | −3.87 |
| GO:0051897 | GO Biological processes | Positive regulation of protein kinase B signaling | 4 | 20.00 | −4.91 | −2.92 |
| GO:0019904 | GO Molecular functions | Protein domain specific binding | 5 | 35.71 | −4.45 | −2.58 |
| GO:0072507 | GO Biological processes | Divalent inorganic cation homeostasis | 4 | 18.18 | −2.92 | −1.26 |
| GO:0001568 | GO Biological processes | Blood vessel development | 4 | 18.18 | −2.31 | −0.69 |
“Count” is the number of genes in the user-provided lists with membership in the given ontology term. “%“ is the percentage of all of the provided genes that are found in the given ontology term (only input genes with at least one ontology term annotation are included in the calculation). “Log10(P)” is the p-value in log base 10. “Log10(q)” is the multi-test adjusted p-value in log base 10.