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. 2021 Apr 30;11:9390. doi: 10.1038/s41598-021-88789-1

Table 4.

Relative risk of specific cancers in patients with keloids, stratified by gender.

Variables All Males Females
Cancer Crude RR (95% CI) P value Adjusted RRa (95% CI) P value Crude RR (95% CI) P value Adjusted RRa (95% CI) P value Crude RR (95% CI) P value Adjusted RRa (95% CI) P value
Esophageal cancer 0.68 (0.35–1.33) 0.2575 0.67 (0.34–1.30) 0.2337
Colon cancer 0.68 (0.53–0.88) 0.0031 0.66 (0.51–0.86) 0.0016 0.71 (0.48–1.03) 0.0728 0.66 (0.45–0.96) 0.0316 0.66 (0.47–0.93) 0.0184 0.66 (0.47–0.94) 0.0196
Liver cancer 0.74 (0.57–0.98) 0.0327 0.73 (0.56–0.96) 0.0251 0.83 (0.56–1.22) 0.3491 0.80 (0.54–1.17) 0.2527 0.67 (0.45–0.98) 0.0416 0.67 (0.46–0.99) 0.0440
Pancreatic cancer 1.72 (0.99–2.98) 0.0555 1.66 (0.95–2.88) 0.0730 1.20 (0.48–2.99) 0.6940 1.11 (0.44–2.76) 0.8295 2.18 (1.08–4.41) 0.0296 2.19 (1.08–4.42) 0.0293
Melanoma 1.40 (0.59–3.31) 0.4424 1.39 (0.59–3.29) 0.4554 1.60 (0.50–5.10) 0.4263 1.47 (0.46–4.71) 0.5130 1.20 (0.33–4.36) 0.7811 1.25 (0.34–4.55) 0.7338
Skin cancer 1.73 (1.13–2.63) 0.0110 1.73 (1.13–2.63) 0.0112 2.29 (1.24–4.24) 0.0081 2.16 (1.17–4.00) 0.0139 1.37 (0.76–2.46) 0.2961 1.43 (0.79–2.57) 0.2329
Breast cancer 0.58 (0.43–0.78) 0.0003 0.58 (0.43–0.78) 0.0003
Prostate cancer 0.57 (0.33–0.98) 0.0406 0.48 (0.28–0.83) 0.0083
Kidney cancer 0.65 (0.29–1.45) 0.2933 0.66 (0.30–1.47) 0.3116
Thyroid cancer 0.76 (0.48–1.22) 0.2604 0.77 (0.48–1.23) 0.2690 0.79 (0.49–1.3) 0.3571 0.79 (0.49–1.3) 0.3591
Hodgkin’s lymphoma 0.50 (0.06–4.00) 0.5139 0.51 (0.06–4.07) 0.5242
Non-Hodgkin’s lymphoma 0.92 (0.51–1.64) 0.7748 0.92 (0.51–1.64) 0.7781 1.47 (0.74–2.93) 0.2759 1.48 (0.74–2.95) 0.2662

RR relative risk, 95% CI 95% confidence interval.

aModel adjusted for age group, gender, and the residential region using a Cox proportional-hazards regression model.