Table 6.
Interacting effects of keloids and chronic pancreatitis on the development of pancreatic cancer in female patients with keloids.
| Variables | N | Pancreatic cancer | Crude RR (95% CI) | P-value | Adjusted RRa (95% CI) | P-value | P for interactionb | |
|---|---|---|---|---|---|---|---|---|
| Keloids | Chronic pancreatitis | 0.5695 | ||||||
| No | No | 42,979 | 20 | Reference | Reference | |||
| Yes | No | 10,728 | 11 | 2.20 (1.06–4.60) | 0.0353 | 2.20 (1.05–4.60) | 0.0355 | |
| No | Yes | 85 | 2 | 50.56 (11.82–216.33) | < 0.0001 | 22.34(5.06–98.65) | < 0.0001 | |
| Yes | Yes | 34 | 1 | 63.22 (8.49–470.95) | < 0.0001 | 23.67(3.10–180.78) | 0.0023 |
RR relative risk, CI confidence interval.
aModel adjusted for age group, gender, and the residential region, liver cirrhosis and diabetes mellitus using a Cox proportional-hazards regression model.
bInteractions between keloid cases and chronic pancreatitis were calculated using the Cox proportional hazards regression model with an added interaction term for keloid cases by chronic pancreatitis and covariates.