Table 7.
Comparison of optic disc and optical coherence tomography parameters in eyes of the temporal visual field defect group in terms of presence of β-zone PPA progression.
| Variable | Enlargement in β-zone PPA (N, 21) | No Enlargement in β-zone PPA (N, 14) | P value | |
|---|---|---|---|---|
| Manually measured cup to disc ratio, mean (SD) | 0.74 (0.19) | 0.60 (0.20) | 0.058 | |
| Tilt ratio, mean (SD) | 1.35 (0.16) | 1.61 (0.22) | < 0.001 | |
| Rotation angle, mean (SD), ° | 3.99 (21.38) | 10.22 (10.95) | 0.275 | |
| Area of Initial β-zone PPA, mean (SD), pixel | 90,192.8 (50,250.9) | 22,820.5 (20,504.0) | < 0.001 | |
| Change of β-zone PPA over years, mean (SD), pixel/year | 5249.8 (3522.5) | 479.4 (301.5) | < 0.001 | |
| Direction of β-zone PPA enlargement (No. (%)) (Inferotemporal/ Temporal/ Superonasal / Superotemporal) | 10 / 7/ 3/ 1 (47.6%/ 33.3%/ 14.3%/ 4.8%) | NA | ||
| Optic disc parameters | Rim area, mean (SD) | 1.79 (0.86) | 1.16 (0.50) | 0.018 |
| Disc area, mean (SD) | 3.46 (1.62) | 2.05 (0.62) | 0.002 | |
| Average cup to disc ratio, mean (SD) | 0.89 (0.21) | 0.75 (0.25) | 0.071 | |
| Vertical cup to disc ratio, mean (SD) | 0.82 (0.25) | 0.68 (0.33) | 0.162 | |
| Cup volume, mean (SD) | 0.32 (0.29) | 0.27 (0.22) | 0.633 | |
| Parapapillary RNFL thickness (μm) | Average, mean (SD) | 90.49 (16.49) | 85.79 (15.98) | 0.415 |
| Superior, mean (SD) | 99.92 (24.85) | 86.55 (23.61) | 0.125 | |
| Nasal, mean (SD) | 82.23 (23.86) | 69.17 (23.83) | 0.126 | |
| Inferior, mean (SD) | 89.63 (25.04) | 105.45 (25.63) | 0.082 | |
| Temporal, mean (SD) | 90.22 (22.06) | 82.48 (24.34) | 0.342 | |
| GCIPL thickness (μm) | Average, mean (SD) | 80.22 (11.43) | 77.35 (8.73) | 0.462 |
| Minimum, mean (SD) | 61.67 (24.09) | 67.83 (16.15) | 0.435 | |
| Superior, mean (SD) | 74.25 (18.40) | 73.96 (12.49) | 0.962 | |
| Superonasal, mean (SD) | 85.80 (17.15) | 79.01 (18.80) | 0.327 | |
| Inferonasal, mean (SD) | 82.15 (14.54) | 79.57 (13.67) | 0.633 | |
| Inferior, mean (SD) | 70.71 (16.23) | 75.04 (8.51) | 0.387 | |
| Inferotemporal, mean (SD) | 81.51 (19.84) | 78.50 (9.16) | 0.610 | |
| Superotemporal, mean (SD) | 86.96 (19.43) | 77.56 (9.45) | 0.116 | |
Progression of β-zone PPA was defined with a change of β-zone PPA area over 1000 pixel /year.
PPA peripapillary atrophy, NA not available, RNFL retinal nerve fiber layer, GCIPL ganglion cell inner plexiform layer.
Values obtained from optical coherence tomography was corrected with the Littmann’s formula.
Student’s t test.
Bold font indicates significant P values (P < 0.05).
aBonferroni correction for multiple measurement comparison was applied, and a level of significance was set at 0.002 (0.05/23).