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. 2021 Apr 30;11:9362. doi: 10.1038/s41598-021-88703-9

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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p-ERK staining in clinical angiosarcoma samples and impact on survival. A tissue microarray with 60 unique clinically annotated angiosarcoma patient samples was stained for phospho-ERK. 26 (44%) stained positive, 27 (45%) stained negative, and 7 (12%) had focal staining (A,B). There was no correlation between phospho-ERK staining and overall survival between cases with low (0–1) phospho-ERK and high (2–5) phospho-ERK (C, p = 0.88). Unedited images were formatted in Adobe Photoshop 2020 (https://www.adobe.com/) to create the figure layout. Survival was assessed using the Kaplan Meier method and log rank test in SPSS (statistical software, IBM SPSS Statistics Version 22, Armonk, NY, https://www.ibm.com/).