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. 2021 Apr 30;7:88. doi: 10.1038/s41420-021-00470-8

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — A qPCR analysis on mRNA expression of SIRT4 in 9 normal liver biopsies and 30 pairs of HCC tumor and their adjacent non-tumor tissues. B SIRT4 protein expression was slightly increased in HCC tumors than their adjacent non-tumor counterparts. Statistically significant differences are denoted by asterisks above the bars, ***p < 0.0001, *p < 0.01.