Table 1.
Observed overall frequency of mutations in pfcrt and pfmdr1
| Gene | Mutations | Wild type(%, 95% CI) | Mutation(%, 95% CI) | Mixed type(%, 95% CI) | Total |
|---|---|---|---|---|---|
| pfcrt | C72S | 104(100.00, 1.00–1.00) | 0(0.00, 0.00–0.00) | 0(0.00, 0.00–0.00) | 104 |
| M74I | 91(87.5, 0.81–0.94) | 10(9.62, 0.039–0.15) | 3(2.88, − 0.004 to 0.062) | 104 | |
| N75E | 91(87.5, 0.81–0.94) | 10(9.62, 0.039–0.15) | 3(2.88, − 0.004 to 0.062) | 104 | |
| K76T | 91(87.5, 0.81–0.94) | 10(9.62, 0.039–0.15) | 3(2.88, − 0.004 to 0.062) | 104 | |
| I356T | 70(89.74, 0.39–0.55) | 5(6.41, 0.09–0.120) | 3(3.84, − 0.005 to 0.082) | 78 | |
| pfmdr1 | N86Y | 99(93.40, 0.89–0.98) | 5(4.72, 0.006–0.088) | 2(1.89, − 0.007 to 0.045) | 106 |
| Y184F | 37(34.91, 0.26–0.44) | 50(47.17, 0.38–0.57) | 19(17.92, 0.11–0.25) | 106 |
Mutations are shown in underline and bold