TABLE 1.
Feature | Presentation |
---|---|
Asymptomatic | 50%‐80% |
Abnormal liver enzymes | 30% |
Hepatomegaly or splenomegaly | On radiological examination, 50% |
Detected clinically, <15%‐20% | |
Symptoms | Abdominal pain, 15% |
Pruritus and jaundice, <5% | |
Cirrhosis | 6%‐8% |
Portal hypertension severe liver dysfunction esophageal varices | 3%‐18% rare up to 78% of cases with portal hypertension |
Advanced disease requiring transplantation | 0.012% of all liver transplants in the United States |
Reproduced with permission from Journal of Clinical and Translational Hepatology. 1 Copyright 2013, Creative Commons Attribution 4.0.