TABLE 2.

Main Differential Diagnosis of Hepatic Sarcoidosis

Condition	Histology	Associated Findings
Sarcoidosis	Well‐differentiated noncaseating granulomas	Pulmonary adenopathy
		Pulmonary interstitial disease
Primary biliary cholangitis	Poorly differentiated noncaseating granulomas	Positive anti‐mitochondrial antibody
		No pulmonary hilar adenopathy
PSC	“Onion skin” periductal fibrosis	Association with IBD
		Typical magnetic resonance cholangiography findings
Drug‐induced hepatic granulomas	Variable, depending on drug; presence of eosinophils in granulomas suggests diagnosis	Pertinent medication history, including recent antibiotics

Reproduced from Clinics in Liver Disease. ¹⁷ Copyright 2019, Elsevier Inc.