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. 2021 May 1;11(4):e401. doi: 10.1002/ctm2.401

FIGURE 5.

FIGURE 5

Kaplan‐Meier analyses for CN gains versus no gains of chr3q27.1‐q27.2 and CN loss versus no loss of chr18q11.2‐12 in Q‐CROC‐01, Sveen et al, and CAIRO2 cohorts. CN gain of chr3q27.1‐27.2 was tested for PFS association in (A) Q‐CROC‐01 liver metastasis (n = 94), (B) Sveen et al liver metastasis cohort (n = 45), (C) CAIRO2 primary tumor samples (n = 133), and (D) Q‐CROC‐01 CRC primary tumors (n = 44). CN loss of chr18q11.2‐12.1 association with a longer PFS was tested in (E) Q‐CROC‐01 CRC primary tumors (n = 44), (F) Q‐CROC‐01 CRC primary tumors from the sub‐group of patients treated with bevacizumab (n = 33), (G) Q‐CROC‐01 liver metastasis (n = 94), (H) Q‐CROC‐01 liver metastases from patients treated with bevacizumab (n = 74), and (I) Sveen et al liver metastases cohort (n = 45)