TABLE 1.
Demographic and clinical characteristics of the study population (n = 33)
|
AP (n = 9) |
RP (n = 9) |
HS (n = 15) |
p‐value | |
|---|---|---|---|---|
| Age (years old) | 36.9 ± 1.4 | 37.9 ± 1.1 | 36. 4 ± 1.6 | NS |
| Male | 7 (77.7) | 6 (66.6) | 6 (40) | NS |
| Index CAI | 11.0 ± 1.3 | 1.7 ± 0.6 | N/A | <0.05 |
| Montreal A (age at onset) | ||||
| A1 (16) | None | None | N/A | NS |
| A2 (17–40) | 7 (77.7) | 6 (66.6) | ||
| A3 (41) | 2 (22.2) | 3 (33.3) | ||
| Montreal Score Extensive | ||||
| E1 ulcerative proctitis | None | None | N/A | NS |
| E2 left‐sided UC | None | None | ||
| E3 extensive UC | 9 (100) | 9 (100) | ||
| Montreal Score Severity | ||||
| S0 silent colitis | None | 9 (100) | N/A | NS |
| S1 mild colitis | None | None | ||
| S2 moderate colitis | None | None | ||
| S3 severe colitis | 9 (100) | None | ||
| Endoscopy Mayo Score | ||||
| 0 | NONE | N/A | N/A | N/A |
| 1 | NONE | |||
| 2 | NONE | |||
| 3 | 9 (100) | |||
| Frequency of bowel movements | ≥ 10 | 2 to 4 | 1 to 2 | NS |
| Presence of blood in stools | 9 (100) | None | None | NS |
| Time (years) from diagnosis | ||||
| ≥10 | 8 (88.8) | 6 (66.6) | N/A | NS |
| ≤10 | 1 (11.1) | 3 (33.3) | ||
| Currently smoking | 2 (22.2) | None | None | N/A |
| Medication use | ||||
| Mesalazine | None | 6 (66.6) | N/A | NS |
| Corticosteroids | 2 (22.2) | 2 (22.2) | ||
| Infliximab | none | 1 (11.1) | ||
| No treatment | 7 (77.7) | None | ||
| Fecal calprotectin (μg/g) | 480.1 ± 13.7 | 99.6 ± 8.9 | 21.6 ± 4.3 | p < 0.05 |
Quantitative data were resumed as mean ± SD and qualitative data as n (%). Statistical analysis was performed with a two‐way U‐Mann Whitney and Fisher's test, as appropriate.
Abbreviations: AP, active pancolitis; HS, healthy subjects; N/A, not applicable; NS, non‐significant; RP Remission pancolitis.