TABLE A6.

Diagnostic performance of Bilophila, Fusobacterium, Faecalibacterium, and Roseburia in discriminating Pancolitis‐related conditions

	AUC	Se (%)	Sp (%)	PPV (%)	NPV (%)
AP vs. HS
Bilophila	0.917	80	100	100	83
Fusobacterium	0.955	90	100	100	90
Faecalibacterium	0.222	0	80	0	44
Roseburia	0.237	0	90	0	47
AP vs. RP
Bilophila	0.917	80	100	100	83
Fusobacterium	0.955	90	100	100	90
Faecalibacterium	0.206	10	10	10	10
Roseburia	0.237	0	90	0	47
RP vs. HS
Bilophila	0.000	N/A	100	N/A	50
Fusobacterium	0.000	N/A	100	N/A	50
Faecalibacterium	0.237	90	0	47	0
Roseburia	0.400	40	60	50	50

Cutoffs. HS vs. AP discrimination: Bilophila (10%), Fusobacterium (10%), Faecalibacterium (45%), Roseburia (20%). AP vs RP discrimination: Bilophila (10%), Faecalibacterium (40%), Roseburia (20%). HS vs RP discrimination: Bilophila (5%), Fusobacterium (5%), Faecalibacterium (20%), Roseburia (10%).

Abbreviatures: AP, Active Pancolitis; AUC, Area Under the Curve; HS, Healthy Subjects; N/A, non‐applicable; NPV, Negative Predictive Value; PPV, Positive Predictive Value; RP, Remission Pancolitis; Se, Sensitivity; Sp, Specificity. Bold letters and values indicates the most abundant and have statistical significance.