FIGURE 1.

USP35 knockdown inhibits lung cancer cell growth, colony formation and tumor progression. A, Relative USP35 mRNA level in ADC, SCC and corresponding ANT tissues (n = 10). B, Relative USP35 mRNA level in normal human lung epithelial cell lines and lung cancer cell lines (n = 6). C, Representative immunoblots of USP35 and the quantitative data (n = 6). D, Relative USP35 protein level in lung cancer cell lines with or without shUSP35 infection (n = 6). E, Cell viability data from CCK‐8 assay (n = 5). F, Colony formation (n = 6). G, Tumor volumes at indicating times in tumor xenografts models (n = 6). H, Tumor weights at day 25 after cell inoculation (n = 6). Data are shown as mean ± SD, *P < .05 versus the matched group