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. 2021 May 1;21:484. doi: 10.1186/s12885-021-08208-6

Table 2.

Efficacy of CT lymph node MAD and/or serum SCC-Ag in judging retroperitoneal lymph node metastasis in patients with locally advanced cervical squamous cell carcinom

Group Case Pathological results Accuracy (%) Sensitivity(%) Specificity (%) Youden index
Positive Negative
CT lymph node MAD ≥1.0 cm + SCC-Ag ≥ 5.2 ng/mL 24 24 0 75.71* 58.54 100.0* 0.59*
CT lymph node MAD ≥1.0 cm 40 33 7 72.09 66.0 80.56 0.47
SCC-Ag ≥ 5.2 ng/mL 39 30 9 71.43 73.17 68.97 0.42

CT computed tomography, MAD minimum axial diameter, SCC-Ag Squamous cell carcinoma antigen. *P  < 0.05 vs. the CT lymph node MAD ≥1.0 cm group and SCC-Ag ≥ 5.2 ng/mL group