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. 2021 Apr 4;8(4):571–581. doi: 10.1002/mdc3.13193

TABLE 3.

Univariate multinomial logistic regression models comparing demographic, psychiatric, clinical, and global cognitive characteristics for anxiety disorder NOS, DSM‐IV diagnosable anxiety disorders, and no anxiety groups

Variable Anxiety NOS vs. no anxiety OR (95% CI) P Anxiety NOS vs. DSM Anxiety OR (95% CI) P DSM anxiety vs. no anxiety OR (95% CI) P
Demographic, clinical and global cognitive characteristics measured in total sample (n = 156)
Sex a 2.44 (1.02–5.85) 0.046* 0.83 (0.32–2.15) 0.696 2.95 (1.37–6.35) 0.006**
Age 0.98 (0.93–1.03) 0.467 1.01 (0.96–1.07) 0.634 0.97 (0.93–1.01) 0.967
SMMSE b 1.02 (0.76–1.37) 0.879 0.69 (0.47–1.02) 0.065 1.48 (1.06–2.07) 0.020*
PD‐CRS b 0.98 (0.95–1.02) 0.289 0.99 (0.95–1.03) 0.590 0.99 (0.96–1.02) 0.604
HAM‐D b 1.28 (1.14–1.44) <0.001*** 0.86 (0.77–0.95) 0.003** 1.50 (1.32–1.70) <0.001***
HAM‐A b 1.27 (1.13–1.42) <0.001*** 0.87 (0.78–0.97) 0.009** 1.46 (1.30–1.65) <0.001***
PDQ‐8 b 1.31 (1.06–1.61) 0.013* 0.89 (0.72–1.10) 0.291 1.47 (1.21–1.78) <0.001***
MDS‐UPDRS Total b , c 1.75 (0.71–4.32) 0.221 0.65 (0.24–1.76) 0.369 2.70 (1.19–6.14) 0.017*
MDS‐UPDRS‐I b , c 4.24 (1.70–10.57) 0.002** 0.61 (0.22–1.68) 0.340 6.95 (2.95–16.29) <0.001***
MDS‐UPDRS‐II b 0.41 (0.17–1.03) 0.059 0.95 (0.87–1.03) 0.222 1.07 (1.00–1.15) 0.061
MDS‐UPDRS‐III b 0.99 (0.95–1.04) 0.719 0.97 (0.92–1.02) 0.217 1.02 (0.99–1.07) 0.235
MDS‐UPDRS‐IV b 1.38 (1.15–1.64) <0.001*** 1.19 (1.01–1.42) 0.044* 1.15 (0.97–1.37) 0.108
Years education b 0.96 (0.87–1.06) 0.404 0.94 (0.84–1.05) 0.290 1.02 (0.93–1.12) 0.683
LEDD b 1.00 (1.00–1.00) 0.054 1.00 (1.00–1.00) 0.018* 1.00 (1.00–1.00) 0.383
Psychiatric characteristics measured in subsample (n = 82)
PAS b 1.18 (1.02–1.36) 0.024* 0.92 (0.81–1.05) 0.224 1.28 (1.14–1.43) <0.001***
Persistent anxiety b 1.28 (1.03–1.60) 0.030* 0.91 (0.73–1.13) 0.382 1.41 (1.20–1.66) <0.001***
Episodic anxiety b 1.52 (1.02–2.26) 0.040* 0.83 (0.58–1.19) 0.311 1.83 (1.36–2.46) <0.001***
Avoidance behavior b 1.22 (0.77–1.92) 0.386 0.79 (0.51–1.23) 0.298 1.54 (1.14–2.08) 0.005**
LSAS b 1.04 (1.01–1.08) 0.024* 0.98 (0.95–1.01) 0.329 1.06 (1.03–1.09) <0.001***
Fear or anxiety b 1.07 (1.00–1.15) 0.044* 0.96 (0.90–1.02) 0.212 1.12 (1.06–1.18) <0.001***
Avoidance behavior b 1.06 (0.98–1.13) 0.139 0.96 (0.89–1.02) 0.199 1.10 (1.05–1.16) <0.001***
SAS b 0.18 (0.29–1.06) 0.058 0.95 (0.83–1.09) 0.477 1.21 (1.09–1.35) <0.001***

Univariate multinomial logistic regressions were conducted to compare current DSM‐IV Anxiety, Anxiety NOS and no anxiety disorder groups. Odds ratios (OR) and 95% confidence intervals (CI) are presented.

a

Male was the reference category.

b

Adjusted for age and sex.

c

Scores dummy‐coded using median splits.

*

P < 0.05.

**

P < 0.01.

***

P < 0.001.

SMMSE, Standardized Mini Mental State Examination; PD‐CRS, Parkinson's Disease Cognitive Rating Scale; HAM‐D, Hamilton Depression Rating Scale; HAM‐A, Hamilton Anxiety Rating Scale; PDQ‐8, Parkinson's Disease Questionnaire; MDS‐UPDRS, Movement Disorder Society Unified Parkinson's Disease Rating Scale; LEDD, levodopa equivalent daily dose; PAS, Parkinson's Anxiety Scale; LSAS, Liebowitz Social Anxiety Scale; SAS, Starkstein Apathy Scale.