Table 2.
Comparison of clinical factors in patients with asthma in two groups and in patients with vitamin D insufficiency and patients with vitamin D deficiency
| Variables | Case | Control | P1 | P2 | P3 | ||||
|---|---|---|---|---|---|---|---|---|---|
| Total (n=66) | Insufficient (n=33) | Deficient (n=33) | Total (n=66) | Insufficient (n=33) | Deficient (n=33) | ||||
| ACT score | |||||||||
| Before | 11.26±3.66 | 11.73±3.56 | 10.79±0.65 | 11.69±3.75 | 11.58±3.62 | 11.81±3.94 | 0.307 | 0.923 | 0.504 |
| 3 months later | 13.30±4.51 | 13.18±4.65 | 13.42±4.44 | 11.45±3.63 | 11.61±3.74 | 11.78±3.57 | 0.812 | 0.752 | 0.011 |
| P4 | <0.001 | 0.014 | 0.002 | 0.486 | 0.956 | 0.236 | |||
| 25(OH)D (ng/ml) | |||||||||
| Before | 17.04±6.42 | 23.42±2.64 | 11.29±0.79 | 17.17±6.59 | 23.64±3.26 | 11.36±0.75 | <0.001 | <0.001 | 0.862 |
| 3 months later | 34.88±8.04 | 36.36±11.33 | 33.54±2.68 | 17.34±6.17 | 23.43±2.96 | 11.88±0.71 | 0.184 | <0.001 | <0.001 |
| P4 | <0.001 | <0.001 | <0.001 | 0.102 | 0.167 | 0.054 | |||
| FVC (%) | |||||||||
| Before | 79.76±9.17 | 79.27±9.37 | 81.67±7.63 | 79.03±10.47 | 80.27±9.33 | 79.91±10.23 | 0.405 | 0.117 | 0.589 |
| 3 months later | 81.29±7.13 | 80.91±6.68 | 81.52±9.95 | 80.47±9.59 | 81.06±10.53 | 80.88±10.55 | 0.922 | 0.052 | 0.536 |
| P4 | 0.098 | <0.001 | 0.125 | 0.166 | 0.107 | 0.506 | |||
| FEV1 (%) | |||||||||
| Before | 71.76±7.70 | 73.52±8.01 | 70.00±7.07 | 72.12±8.04 | 71.12±7.25 | 73.12±8.76 | 0.069 | 0.300 | 0.791 |
| 3 months later | 74.17±10.16 | 72.85±15.77 | 75.48±9.98 | 72.55±8.82 | 73.09±9.60 | 72.00±8.08 | 0.343 | 0.694 | 0.041 |
| P4 | 0.130 | 0.796 | 0.003 | 0.658 | 0.172 | 0.376 | |||
| FEV 1 / FVC (%) | |||||||||
| Before | 74.89±5.99 | 75.58±5.17 | 74.21±6.73 | 73.95±6.54 | 73.97±6.93 | 73.94±6.22 | 0.381 | 0.984 | 0.391 |
| 3 months later | 80.08±11.13 | 80.15±10.54 | 80.00±11.85 | 75.37±12.09 | 77.44±10.83 | 73.36±6.43 | 0.958 | 0.160 | 0.022 |
| P4 | <0.001 | 0.006 | 0.008 | 0.447 | 0.322 | 0.531 | |||
Abbreviate: ACT score: Asthma Control Test score; FEV1: Forced Expiratory Volume in one second; FVC: Forced Vital Capacity
P1: The significant level of comparison two subgroups insufficient vitamin D with deficient in Case group
P2: The significant level of comparison two subgroups insufficient vitamin D with deficient in Control group
P3: The significant level of comparison two groups study (Case group with Control group)
P4: The significant level of comparison between before and 3 months later in each groups and subgroups