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Loss of Slit2 alone does not alter islet architecture. Immunofluorescence staining of β cells (insulin, red) and α cells (glucagon, cyan) in E18.5 control, Ins2-Cre; Robo1−/−; Robo2flx/flx, and Slit2 mice. Scale bars, 50 μm. n = 3 for all genotypes analyzed.
