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. Author manuscript; available in PMC: 2022 Apr 1.
Published in final edited form as: Am J Cardiol. 2020 Dec 29;144:52–59. doi: 10.1016/j.amjcard.2020.12.062

Table 5 -.

Univariate Outcomes stratified by low and high inappropriate dosing classification

Outcome Appropriate Dose (N=7303) Inappropriate Low Dose (N=1071) Inappropriate High Dose (N=202) P value
Stroke/ Transient Ischemic Attack /Embolism 81 (1.1%) 16 (1.5%) 3 (1.5%) 0.50
Major Bleed 121 (1.7%) 21 (2.0%) 7 (3.5%) 0.13
Clinically relevant Non-Major Bleed 152 (2.1%) 22 (2.1%) 10 (5.0%) 0.02
Any Bleed 531 (7.2%) 84 (7.8%) 26 (12.9%) 0.01
Intracerebral Hemorrhage 112 (1.5%) 17 (1.6%) 6 (2.9%) 0.26