Figure 1.

Effects of CUMS on the behaviors of MCAO rats. (a) The study schedule and behavioral testing time frames. (b) Representative heat maps of the immobility duration of each group in the OFT. (c) Dynamic variations in the weight of experimental subjects. (d) Changes in sucrose preference after a three-week stress period. (e) Pretreatment differences in immobility between groups. (f) Rearing counts of each group in the OFT. (g) Variations in distance travelled after chronic stress. (h) Changes in average speed of subjects in various groups after a three-week stress period. One-way ANOVA followed by Tukey's multiple comparison tests and repeated measures ANOVA were used for analysis. n = 21 per group. ^∗p < 0.05, ^∗∗p < 0.005, ^∗∗∗p < 0.0005, and ^∗∗∗∗p < 0.0001.