TABLE 2.
Immortalized human fallopian tube fimbrial epithelial cell lines
| Cell line name | Method of immortalization | Gene alterations | PMID |
|---|---|---|---|
| FT33‐TAg | FTE+hTERT+SV40 large T plus small T | hTERT gain, P53 and RB loss | 21502498 |
| FT190 | FTE+hTERT+SV40 large T | hTERT gain, P53 and RB loss | 22936217 |
| FT194 | FTE+hTERT+SV40 large T | hTERT gain, P53 and RB loss | 22936217 |
| FE25 | FTE+HPV16 E6/E7+hTERT | P53 and RB loss, hTERT gain | 26363031 |
| FT282 | FTE+hTERT+TP53R175H | hTERT gain, TP53 GOF mutation | 24366882 |
| FT282‐c11 | FTE+hTERT+TP53R175H (Clonal) | hTERT gain, TP53 GOF mutation | 30459449 |
| FT33‐shp53‐R24C | FTE+hTERT+p53 shRNA+CDK4R24C | TP53 knockdown, Rb pathway loss | 21502498 |
| FT237 | FTE+hTERT+p53 shRNA+CDK4R24C | hTERT gain, TP53 knockdown, RB pathway loss | 22936217 |
| FT240 | FTE+hTERT+p53 shRNA+CDK4R24C | hTERT gain, TP53 knockdown, RB pathway loss | 22936217 |
| FT246 | FTE+hTERT+p53 shRNA+CDK4R24C | hTERT gain, TP53 knockdown, RB pathway loss | 22936217 |
| FT240‐R175 | FTE+hTERT+TP53R175H+CDK4R24C | hTERT gain, TP53 GOF mutation, RB pathway loss | 32471985 |
| FT240‐R248 | FTE+hTERT+TP53R248+CDK4R24C | hTERT gain, TP53 GOF mutation, RB pathway loss | 32471985 |
| FT240‐R273 | FTE+hTERT+TP53R273+CDK4R24C | hTERT gain, TP53 GOF mutation, RB pathway loss | 32471985 |
Abbreviation: GOF, gain of function.