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. 2021 May 1;11:81. doi: 10.1186/s13578-021-00590-9

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 6 — Analysis of DEGs that are critical for NMJ maturation. a The DEGs were enriched in the oxidation–reduction process and ion transport pathways. b The PPI network of the DEGs was constructed by Cytoscape. c Selected gene sets related to the NMJ. d, e Selected enriched gene sets from the GSEA revealed that the genes in the synapsis and regulation of presynapse organization gene sets are inactive in adult mice compared with P0 mice