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Estimated sample sizes (means and confidence intervals) needed to detect a given effect size for a given trial duration and assessment frequency in the London cohort
| 50% Effect Size | 30% Effect Size | |||
|---|---|---|---|---|
| Frequency | 2 y | 3 y | 2 y | 3 y |
| 6 mo | 151 (79‐392) | 54 (28‐141) | 419 (220‐1090) | 150 (79‐389) |
| Annual | 189 (99‐490) | 75 (40‐196) | 524 (275‐1362) | 210 (110‐545) |
Note: estimates are per treatment arm.
