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A male patient with Ectrodactyly-ectodermal dysplasia-clefting (EEC) syndrome. He had constant epiphora due to right sided punctal agenesis that resolved with CJDCR at the age of 18 years. Systemic disorders included cleft lip and palate, syndactyly, dental abnormalities, midface hypoplasia, and hearing disorders. a The patient at infancy, showing ectrodactyly. b Same patient, at age 18 years, showing absent lower punctum on the right side (punctal agenesis), and a Lester-Jones tube
