Fig. 8.

CTSL1 inhibitor treatment reversed the oncogenic effects of lnc-CTSLP8 in vitro and in vivo. a Cell viability assay of SKOV3-CTSLP8-OE cell lines treated by CTSL1 inhibitor Z-FY-DMK, DMSO (negative control), or untreated (blank control). b and c Colony formation in different groups. d and e The invasion and migration of different groups. f Representative bioluminescence image of control and Z-FY-DMK-treated ovarian tumor-bearing mice. g Size of ovarian tumors in different mouse groups. h Quantification of tumor fluorescence intensity and tumor weight. i Survival of tumor-bearing mice in different groups. j Metastasis counts in different groups