Fig. 1.

Disease activity course across different JIA categories. Disease activity was assessed at baseline and 3-month intervals thereafter via the clinical juvenile arthritis disease activity score (cJADAS) and converted to an ordinal scale via validated cut-offs that were established for patients with oligoarthritis and polyarthritis. Children with JIA in ILAR categories other than oligo- or polyarthritis were categorized based on the number of joints affected during the disease course (≤4 or > 4, respectively). Low disease activity: 1.1–1.5 in oligoarthritis or 1.1–2.5 in polyarthritis; moderate disease activity: 1.51–4 or 2.51–8.5; high disease activity: > 4 or > 8.5, respectively