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. 2021 Apr 29;9:e11366. doi: 10.7717/peerj.11366

Table 1. Correlation of recurrence and recurrence-free-survival (RFS) with patient demographics and clinicopathological characteristics.

Parameter n Recurrence P RFS (P)* D-recurrence P D-RFS (P)*
Age
<53 19 7 0.1279 0.062 5 0.408 0.193
≧53 17 2 2
TNM stage
II 29 5 0.0497 0.033 4 0.1159 0.093
III 7 4 3
T stage
T1 5 1 0.2193 0.11 1 0.8124 0.666
T2 28 6 5
T3 3 2 1
N stage
N0 15 2 0.0643 0.083 2 0.0309 0.053
N1 14 4 2
N2 5 1 1
N3 2 2 2
Differentiation
I 13 5 0.216 0.195 4 0.364 0.327
II 11 3 2
III 12 1 1
ER
Yes 27 7 1 0.855 5 1 0.818
No 9 2 2
PR
Yes 21 5 1 0.919 5 0.6738 0.452
No 15 4 2
HER2
Yes 10 4 0.2262 0.134 3 0.3696 0.237
No 26 5 4
Menopause
Yes 21 5 1 0.754 3 0.4178 0.316
No 15 4 4
Ad chemo TX
Yes 29 8 0.6518 0.374 7 0.3029 0.13
No 7 1 0
Ad rad TX
Yes 23 8 0.1136 0.109 7 0.0343 0.047
No 13 1 0
Ad hor TX
Yes 28 7 1 0.945 5 0.639 0.637
No 8 2 2
Ad tar TX
Yes 10 4 0.2262 0.134 2 1 0.134
No 26 5 5
CTCs
≧4 9 5 0.0262 0.013 4 0.0497 0.029
<4 27 4 3

Notes:

*

Follow-up (days): min = 128; max = 723; mean = 518; median = 536.

Abbreviation: n = number; RFS = recurrence-free survival; D = distant; D-RFS = distant recurrence-free survival; TNM = tumor-node-metastasis; ER = estrogen receptor; PR = progesterone receptor; HER2 = human epidermal growth factor receptor-2; Ad chemo TX = adjuvant chemotherapy; Ad rad TX = adjuvant radiation therapy; Ad hor TX = adjuvant hormonal therapy; Ad tar TX = adjuvant targeted therapy; CTCs = circulating tumor cells.