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. 2021 Apr 28;22:e930733-1–e930733-7. doi: 10.12659/AJCR.930733

Table 1.

Timeline of the insulin dose adjustment and HA1C level.

Date HA1C Diabetes regimens
Baseline 7.3 Detemir 50 units in AM and 50 units in PM, Metformin 1000 mg twice daily, Repaglinide 2 mg before meals, Pioglitazone 15 mg daily
Cancer diagnosed 7.4 Detemir 50 units in AM and 30 units in PM without hypoglycemia episodes. Prandial insulin lispro 5 units was added. Metformin and Repaglinide were discontinued at the beginning of chemotherapy
3 months after cancer diagnosis 7.5 Detemir 50 units in AM and 30 units in PM. Prandial lispro insulin was increased to 15 units with correction lispro ISF 1: 25. CGM was started
6 months after cancer diagnosis 8.7 Detemir 50 units in AM and 40 units in PM with correction lispro ISF 1: 18 on the first and second days following chemotherapy
10 months after cancer diagnosis 8.5 Detemir 50 units in AM and 45 units in PM on the chemotherapy day and 40 units on the following night. ISF 1: 18 on both days

ISF – insulin sensitivity factor; CGM – continuous glucose monitoring.