. 2021 Mar 29;6(1):e26621. doi: 10.2196/26621

Table 5.

Comparisons of baseline-adjusted health outcome means between groups at 3 and 6 months.

Groups			Intervention									Control
			Completed ≥1 module				All intervention
			n		Mean^a (95% CI)		n		Mean (95% CI)		n			Mean (95% CI)
HbA_1c^b
	3 months^c	36		7.6 (7.2 to 8.0)		106		8.0 (7.7 to 8.4)		77			8.2 (8.0 to 8.6)
	6 months^d	25		7.9 (7.3 to 8.5)		95		8.2 (7.8 to 8.6)		69			8.4 (8.1 to 8.9)
BMI
	3 months^e	40		31.3 (30.9 to 31.7)		138		31.7 (31.5 to 32.0)		100			32.1 (31.8 to 32.4)
	6 months^f	33		31.6 (31.1 to 32.0)		120		32.5 (32.2 to 32.8)		81			33.0 (32.7 to 33.4)
SBP^g
	3 months^h	40		124.0 (119.3 to 128.6)		136		126.2 (123.4 to 129.1)		105			126.9 (124.0 to 129.9)
	6 monthsⁱ	32		126.2 (121.7 to 130.8)		122		127.4 (124.6 to 130.2)		83			127.6 (124.5 to 130.7)
DBP^j
	3 months^k	40		72.3 (69.5 to 75.0)		136		74.9 (73.1 to 76.6)		105			75.9 (74.1 to 77.8)
	6 months^l	32		74.0 (71.0 to 77.0)		122		75.0 (73.0 to 77.0)		83			75.4 (73.2 to 77.6)

^aMean: baseline-adjusted sample predicted value.

^bHbA_1c: glycated hemoglobin.

^cIntent-to-treat (ITT) analysis (comparison between intervention and control patients; control-intervention): difference=0.2, 95% CI –0.2 to 0.6; P=.38 (indicates the interaction term left in the model). Per-protocol (PP) analysis: comparison between intervention subjects completing at least one Diabetes Engagement and Activation Platform module (answering postmodule questions) and control patients. PP analysis (control-intervention): difference=0.6, 95% CI 0.1 to 1.1; P=.03.

^dITT analysis (control-intervention): difference=0.3, 95% CI –0.2 to 0.8; P=.27. PP analysis (control-intervention): difference=0.5, 95% CI –0.2 to 1.2; P=.17.

^eITT analysis (control-intervention): difference=0.4, 95% CI 0.0 to 0.8; P=.04 (indicates the interaction term left in the model). PP analysis (control-intervention): difference=1.0, 95% CI 0.5 to 1.4; P<.001.

^fITT analysis (control-intervention): difference=0.5, 95% CI 0.1 to 1.0; P=.02. PP analysis (control-intervention): difference=1.0, 95% CI 0.5 to 1.5; P<.001.

^gSBP: systolic blood pressure.

^hITT analysis (control-intervention): difference=0.7, 95% CI –3.4 to 4.9; P=.73. PP analysis (control-intervention): difference=3.2, 95% CI –2.3 to 8.8; P=.25.

ⁱITT analysis (control-intervention): difference=0.2, 95% CI –4.0 to 4.3; P=.94. PP analysis (control-intervention): difference=0.5, 95% CI –4.9 to 5.9; P=.85.

^jDBP: diastolic blood pressure.

^kITT analysis (control-intervention): difference=1.1, 95% CI –1.4 to 3.6; P=.39. PP analysis (control-intervention): difference=4.3, 95% CI 1.0 to 7.5; P=.01.

^lITT analysis (control-intervention): difference=0.4, 95% CI –2.5 to 3.4; P=.78. PP analysis (control-intervention): difference=1.6, 95% CI –1.9 to 5.1; P=.37.