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. 2021 Mar 29;6(1):e26621. doi: 10.2196/26621

Table 6.

Comparison between groups of change in glycated hemoglobin, BMI, and blood pressure from baseline to 3 and 6 months.

Groups Intervention Control

Completed ≥1 module All interventions

n Meana (95% CI) n Mean (95% CI) n Mean (95% CI)
HbA1cb

Baseline to 3 monthsc 36 –1.8 (–2.4 to –1.3) 106 –1.3 (–1.6 to –1.0) 77 –1.5 (–1.8 to –1.1)

Baseline to 6 monthsd 25 –1.5 (–2.2 to –0.8) 95 –1.1 (–1.5 to –0.8) 68 –1.3 (–1.7 to –0.8)
BMI

Baseline to 3 monthse 40 –0.9 (–1.3 to –0.6) 138 –0.3 (–0.5 to 0.0) 97 0.1 (–0.2 to 0.3)

Baseline to 6 monthsf 33 –0.8 (–1.3 to –0.4) 119 –0.4 (–0.6 to –0.1) 78 0.1 (–0.1 to 0.4)
SBPg

Baseline to 3 monthsh 40 –5.0 (–10.2 to 0.2) 135 –3.8 (–6.5 to –1.2) 101 –1.7 (–4.9 to 1.5)

Baseline to 6 monthsi 32 –1.7 (–6.7 to 3.4) 120 –0.4 (–2.9 to 2.1) 79 –1.1 (–4.2 to 2.1)
DBPj

Baseline to 3 monthsk 40 –5.2 (–8.1 to –2.2) 135 –2.4 (–4.0 to –0.8) 101 –1.3 (–3.1 to 0.6)

Baseline to 6 monthsl 32 –2.6 (–5.9 to 0.8) 120 –0.4 (–2.2 to 1.4) 79 –1.3 (–3.4 to 0.8)

aMean is the model-predicted difference (baseline minus the 3- or 6-month value).

bHbA1c: glycated hemoglobin.

cIntent-to-treat (ITT) analysis (control-intervention): difference=–0.2, 95% CI –0.6 to 0.3; P=.53 (comparison between all intervention and control patients). Per-protocol (PP) analysis (control-intervention): difference=0.3, 95% CI –0.3 to 1.0; P=.29 (comparison between intervention subjects completing at least one DEAP module [answering postmodule questions] and control patients).

dITT analysis (control-intervention): difference=–0.1, 95% CI –0.7 to 0.4; P=.67. PP analysis (control-intervention): difference=0.2, 95% CI –0.6 to 1.1; P=.54.

eITT analysis (control-intervention): difference=0.3, 95% CI 0.0 to 0.7; P=.07. PP analysis (control-intervention): difference=1.0, 95% CI 0.5 to 1.4; P<.001.

fITT analysis (control-intervention): difference=0.5, 95% CI 0.1 to 0.9; P=.02. PP analysis (control-intervention): difference=1.0, 95% CI 0.5 to 1.5; P<.001.

gSBP: systolic blood pressure.

hITT analysis (control-intervention): difference=2.1, 95% CI –1.9 to 6.2; P=.30. PP analysis (control-intervention): difference=3.3, 95% CI –2.8 to 9.4; P=.28.

iITT analysis (control-intervention): difference=–0.7, 95% CI –4.6 to 3.2; P=.73. PP analysis (control-intervention): difference=0.6, 95% CI –5.3 to 6.5; P=.85.

jDBP: diastolic blood pressure.

kITT analysis (control-intervention): difference=1.1, 95% CI –1.3 to 3.6; P=.35. PP analysis (control-intervention): difference=3.9, 95% CI 0.4 to 7.4; P=.03.

lITT analysis (control-intervention): difference=–1.0, 95% CI –3.8 to 1.8; P=.47. PP analysis (control-intervention): difference=1.3, 95% CI –2.7 to 5.3; P=.52.