TABLE 2.
Univariate and multivariate analysis of different prognostic parameters in 199 patients with UCB in SYSUCC
| Variable | All cases | Univariate analysis a | P‐value | Multivariate analysis b | P‐value |
|---|---|---|---|---|---|
| HR (95% CI) | HR (95% CI) | ||||
| Age (years) | |||||
| ≤60 | 102 | 1.0 | .038 | 1.0 | .029 |
| >60 | 97 | 1.657 (1.027‐2.674) | 1.727 (1.058‐2.818) | ||
| Gender | |||||
| Female | 21 | 1 | .174 | ||
| Male | 178 | 1.699 (0.796‐3.624) | |||
| Smoking history | |||||
| No | 92 | 1 | .834 | ||
| Yes | 107 | 1.052 (0.654‐1.692) | |||
| pT status | |||||
| T1 | 46 | 1 | .001 | 1.0 | |
| T2‐T4 | 153 | 3.499 (1.599‐7.656) | 2.338 (1.029‐5.312) | .043 | |
| pN status | |||||
| pN‐ | 158 | 1 | .001 | 1.0 | .001 |
| pN+ | 41 | 3.566 (2.086‐6.098) | 2.541 (1.435‐4.501) | ||
| Histological grade (WHO, 2004) 38 | |||||
| Low grade | 71 | 1 | .001 | 1 | .032 |
| High grade | 128 | 3.044 (1.687‐5.493) | 1.995 (1.060‐3.757) | ||
| ZHX3 | |||||
| Normal expression | 94 | 1 | .001 | 1.0 | .001 |
| Overexpression | 105 | 4.029 (2.361‐6.878) | 2.749 (1.529‐4.941) | ||
| Recurrence | |||||
| No | 112 | 1 | .001 | 1 | .021 |
| Yes | 87 | 2.851 (1.722‐4.720) | 1.914 (1.102‐3.323) | ||
Abbreviations: CI, confidence interval; HR, hazards ratio; UCB, Urothelial carcinoma of the bladder.
a
Univariate Cox regression model.
b
Multivariate Cox regression model.