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. 2021 Mar 30;112(5):1911–1923. doi: 10.1111/cas.14872

TABLE 1.

Clinical characteristics of 77 patients with lung adenocarcinoma in the GSE40419 public database 42

Characteristics No. of patients (%)

Low GPNMB* expression

Patient no. (%)

High GPNMB* expression

Patient no. (%)

P
77 52 (68%) 25 (32%)
EGFR
Wild‐type 58 (75%) 43 (83%) 15 (60%)
All mutants 19 (25%) 9 (17%) 10 (40%) .0267b
L858R 12 (16%) 4 (8%) 8 (32%)
Del19 6 (8%) 4 (8%) 2 (8%)
Others 1 (1%) 1 (1%) 0 (0%)
Age 64.03 ± 9.52 63.31 ± 9.39 65.52 ± 9.80 .3521a
Sex
Female 33 (43%) 22 (42%) 11 (44%) >.999b
Male 44 (57%) 30 (58%) 4 (56%)
Tumor stage
I‐II 61 (79%) 42 (81%) 19 (76%) .5308c
III‐IV 14 (18%) 8 (15%) 6 (24%)
Unclear 2 (3%) 2 (4%) 0 (0%)
Smoking
Yes 43 (56%) 29 (56%) 14 (56%) >.999b
No 34 (44%) 23 (44%) 11 (44%)

P‐value by a: Student t test, b: Fisher's exact test, c: Chi‐square test; *Cut‐off value: log2 T/N = 0.465.